Endocrine Abstracts

Introduction : Type 1 diabetes (T1DM) is an autoimmune disease that commonly affects a young population. Its evolution can be characterized by a frequent occurrence of degenerative complications. Our aims were to study microangiopathic complications, lipid profile, and the presence of other autoimmune diseases in type 1 diabetic patients whose diabetes has been evolving for 10 years or more.Method : This is a descriptive cross-sectional study including T...

Introduction: Obesity poses a significant health risk and is linked to several comorbidities, including diabetes. The aim of our study was to evaluate the impact of obesity on glycemic control in type 2 diabetics.Methods: It was a descriptive and analytical study, conducted in 200 diabetic patients hospitalized at the National Institute of Nutrition of Tunis. Each patient received a biological assessment including glycated hemoglobin (HbA1c) and a glycem...

Introduction: Diabetes in the elderly is often accompanied by other comorbidities, particularly dyslipidemia, which considerably increases the cardiovascular risk in these patients.The aim of our work was to determine the lipid profile in elderly diabetic subjects.Methods: This was a descriptive and analytical study carried out on 100 elderly type 2 diabetics hospitalized in our department for unbalanced diabetes. Each patient unde...

Introduction: Due to the association of hyperuricemia with conventional cardiovascular risk factors, it is difficult to determine whether uric acid is an independent risk factor for the development of renal failure. The objective of this study was to investigate the correlation between uric acid levels and kidney function in type 2 diabetics.Methods: This was a descriptive cross–sectional study carried out from March to September 2017 on 122 diabet...

Introduction: Insulin therapy ( IT) in type 2 diabetes( T2D) is an integral Pharmacologic Approache because of the progressive nature of the disease. Insulin improves glycemic control and reduces the risk of microvascular complications. It’s however associated with weight gain as a side effect which promotes insulinoresistance and cardiovascular morbi–mortality.In this work we evaluated long–term weight gain in insulin–treated pat...

Introduction: Primary biliary cirrhosis and autoimmune hepatitis are two chronic liver diseases. An overlap of the characteristic signs of these two conditions, determining an ‘Overlap syndrome’ can be seen. Type 1 diabetes can be associated with this syndrome due to the autoimmune predisposition.Observation: We report the case of a young type 1 diabetic patient referred to our service for additional management of a glycemic imbalance. This i...

Introduction: Diabetes is the leading cause of end-stage renal disease in Europe (12 to 30%). In the United States, it is the cause of more than half of the cases of this disease. Renal disease is a cardiovascular morbidity and mortality preacher which is three times more common in diabetic patients with diabetic nephropathy (DN). The aim of our study was to describe the factors of cardiovascular risk associated with ND in a group of type 2 diabetes (T2D) Tunisians.<p clas...

Introduction: High blood pressure during pregnancy is associated with various maternal and fetal complications. This risk further complicates the pregnancy of diabetic women.Patients and Methods: We carried out a longitudinal retrospective study including one hundred pregnant women with type 1 and type2 diabetes, recruited from the patients monitored at the national nutrition institute during the period from January to December 2016.<p class="abstext...

Introduction: Diabetic pregnancy is a high risk pregnancy. The objective of our study was to study the clinical-biological profile of pregnant women with gestational diabetes.Methods: It was a retrospective study of 82 pregnant diabetic women admitted to the day hospital of the National Nutrition Institute in Tunis for the management of gestational diabetes. All patients received regular follow-up until delivery.Results: The averag...

Lipid abnormalities are common in diabetic patients, increasing their cardiovascular risk. The aim of our study is to compare the lipid profile between type 1 and type 2 diabetics. This is a retrospective study of 100 patients, half of them have type 1 diabetes (group 1) and the other half have type 2 diabetes (group 2), hospitalized in department A of the National Institute of Nutrition of Tunis between January 2017 and June 2017. Type 2 diabetics were older than type 1 diabe...